HIV Antiretroviral Drugs

People infected with Hiv may benefit from micronutrient supplementation, according to a article published in the February 2007, issue of the American Journal of Clinical Nutrition. The main focus of this article was with Hiv-infected persons not receiving highly active antiretroviral therapy (Haart), but also reports that further study of those receiving Haart may show benefits as well because Haart therapy is shown to deplete many micronutrients in the body.

Hiv medications are relatively easy to procure in industrialized countries, but only 1 in 7 in Asian countries and 1 in 10 in African countries have passage to Hiv antiviral drugs. Micronutrient deficiencies are commonly observed in those with industrialized Hiv disease and are connected with higher risk of disease progression and mortality. In those receiving Haart, immunologic function is restored but these drugs do not eliminate weight loss and wasting. Because of these factors, micronutrient supplementation can be an uncostly way to enhance potential of life and possibly reduce condition care expenditures in those suffering from industrialized stages of Hiv disease as well as those who continue to suffer from disease effects not treated by Haart therapy.

Drugs For Hiv

In one placebo-controlled study, Hiv-infected patients were given Vitamins A, C, and E for six months. At the beginning of the test, all patients had lower levels of these foremost nutrients when compared to a group of Hiv-negative healthy volunteers. At the end of the study, the levels of these nutrients were general in the patients given supplementation and not in the placebo group. The study also showed that the supplemented group had substantially best antioxidant defenses and lower levels of oxidative stress than the placebo group.

Because Hiv medications have a direct corollary on the synthesis and metabolism of micronutrients in the body, restoring these depleted levels straight through dietary supplementation may also furnish ample benefit for those on Haart therapy. A small study showed that greater intake of Vitamin E in adults receiving Haart reduced the outcome of Haart-related complications which comprise body fat redistribution, dyslipidemia and insulin resistance. Other studies have been shown to stimulate glutathione peroxidase activity and discount of oxidative stress.

Such studies demonstrate the principal need for optimal nutritional maintain in Hiv-infected people. It also calls for the need of further studies to furnish further validation and solutions for people not able to receive Haart therapy as well as to maintain and enhance the widespread condition of those who are on Haart therapy. The long-term benefits may be seen in reduced condition care expenditures, around the world, as well as improved potential of life for those suffering from the effects of Hiv infection.

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